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The same 500mcg via nasal spray delivers roughly 200-300mcg systemically

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Lixisenatide, sold under the brand name Adlyxin, belongs to the GLP-1 receptor agonist class and helps manage type 2 diabetes

Reviews describe possible interactions with NMDA receptors, alpha-adrenergic signaling, opioid receptors, and the hypothalamic-pituitary-adrenal axis